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| First Basemen Single-Season Doubles Leaderboard | |
| * - Indicates Hall of Fame |
| Rank | Player | Doubles | PA | Year | Career Leaderboard |
| 1. | John Anderson | 56 | 602 | 1903 | |
| 2. | Bill Mellor | 54 | 613 | 1904 | |
| 3. | Lyman Lamb | 53 | 458 | 1923 | |
| 4. | Bill Kelly | 50 | 625 | 1929 | |
| 5. | Lou Gehrig | 49 | 637 | 1925 | |
| Joe Kelley | 49 | 635 | 1905 | ||
| 7. | Mike Grady | 48 | 602 | 1905 | |
| 8. | Buck Freeman | 47 | 652 | 1905 | |
| Harry Davis | 47 | 647 | 1904 | ||
| 10. | Lou Gehrig | 46 | 628 | 1926 | |
| 11. | Lou Gehrig | 45 | 639 | 1929 | |
| Jimmy Hudgens | 45 | 472 | 1923 | ||
| 13. | Dale Alexander | 44 | 626 | 1929 | |
| Bill Mellor | 44 | 583 | 1905 | ||
| 15. | Bill Kelly | 42 | 611 | 1926 | |
| Mike Grady | 42 | 676 | 1904 | ||
| 17. | Bill Kelly | 41 | 627 | 1928 | |
| Bill Kelly | 41 | 648 | 1924 | ||
| George Sisler | 41 | 655 | 1922 | ||
| Buck Freeman | 41 | 636 | 1904 | ||
| 21. | Paul Waner | 40 | 608 | 1929 | |
| Jimmy Hudgens | 40 | 599 | 1927 | ||
| George Sisler | 40 | 612 | 1924 | ||
| John Anderson | 40 | 674 | 1905 | ||
| Frank Isbell | 40 | 624 | 1904 | ||
| Kitty Bransfield | 40 | 607 | 1904 | ||
| Harry Davis | 40 | 605 | 1903 | ||
| John Anderson | 40 | 558 | 1901 | ||
| 29. | Del Bissonette | 39 | 583 | 1929 | |
| George Sisler | 39 | 654 | 1925 | ||
| Ivy Griffin | 39 | 585 | 1923 | ||
| George Sisler | 39 | 615 | 1921 | ||
| Kitty Bransfield | 39 | 662 | 1905 | ||
| Jake Beckley | 39 | 608 | 1905 | ||
| Joe Kelley | 39 | 605 | 1903 | ||
| 36. | Jimmie Foxx | 38 | 600 | 1929 | |
| Bill Kelly | 38 | 613 | 1927 | ||
| Bill Terry | 38 | 626 | 1926 | ||
| Bill Kelly | 38 | 638 | 1925 | ||
| Lou Gehrig | 38 | 584 | 1924 | ||
| Joe Kelley | 38 | 657 | 1904 | ||
| John Anderson | 38 | 649 | 1904 | ||
| 43. | Jim Bottomley | 37 | 649 | 1922 | |
| 44. | Jimmy Hudgens | 36 | 530 | 1929 | |
| Jimmy Hudgens | 36 | 591 | 1926 | ||
| Jack Fournier | 36 | 594 | 1920 | ||
| Harry Davis | 36 | 680 | 1905 | ||
| Cy Seymour | 36 | 614 | 1905 | ||
| Jake Beckley | 36 | 601 | 1903 | ||
| Kitty Bransfield | 36 | 593 | 1901 | ||
| 51. | Wally Pipp | 35 | 540 | 1925 | |
| Bill Kelly | 35 | 633 | 1923 | ||
| Hal Chase | 35 | 617 | 1913 | ||
| Jack Fournier | 35 | 555 | 1912 | ||
| Fred Luderus | 35 | 680 | 1911 | ||
| Mike Grady | 35 | 604 | 1903 | ||
| Hughie Jennings | 35 | 621 | 1902 | ||
| 58. | George Sisler | 34 | 631 | 1928 | |
| Bill Terry | 34 | 622 | 1928 | ||
| George Sisler | 34 | 617 | 1927 | ||
| Paul Waner | 34 | 616 | 1927 | ||
| Jack Fournier | 34 | 490 | 1919 | ||
| Jack Fournier | 34 | 620 | 1918 | ||
| Jake Daubert | 34 | 605 | 1916 | ||
| Stuffy McInnis | 34 | 613 | 1915 | ||
| Fred Luderus | 34 | 627 | 1914 | ||
| Stuffy McInnis | 34 | 630 | 1912 | ||
| Harry Hooper * | 34 | 602 | 1911 | ||
| 69. | George Grantham | 33 | 593 | 1928 | |
| Jimmy Hudgens | 33 | 576 | 1928 | ||
| Jim Bottomley | 33 | 620 | 1927 | ||
| George Grantham | 33 | 617 | 1927 | ||
| Snake Henry | 33 | 592 | 1925 | ||
| Jim Bottomley | 33 | 649 | 1923 | ||
| Harry Hooper * | 33 | 591 | 1922 | ||
| Ed Konetchy | 33 | 636 | 1917 | ||
| Harry Hooper * | 33 | 643 | 1913 | ||
| 78. | Del Bissonette | 32 | 635 | 1928 | |
| Lou Gehrig | 32 | 668 | 1927 | ||
| Hank Hulvey | 32 | 682 | 1926 | ||
| George Sisler | 32 | 628 | 1926 | ||
| Jim Bottomley | 32 | 616 | 1926 | ||
| Lyman Lamb | 32 | 378 | 1922 | ||
| Gavvy Cravath | 32 | 584 | 1910 | ||
| Dan McGann | 32 | 697 | 1904 | ||
| Sam Dungan | 32 | 635 | 1904 | ||
| Cy Seymour | 32 | 616 | 1904 | ||
| 88. | George Grantham | 31 | 620 | 1926 | |
| Jim Bottomley | 31 | 646 | 1925 | ||
| George Grantham | 31 | 595 | 1924 | ||
| Ivy Griffin | 31 | 585 | 1924 | ||
| Russ Wrightstone | 31 | 585 | 1923 | ||
| George Grantham | 31 | 489 | 1922 | ||
| George Sisler | 31 | 591 | 1918 | ||
| Stuffy McInnis | 31 | 616 | 1914 | ||
| Bill Mellor | 31 | 589 | 1906 | ||
| Tim Jordan | 31 | 376 | 1904 | ||
| Kitty Bransfield | 31 | 522 | 1903 | ||
| Buck Freeman | 31 | 583 | 1902 | ||
| 100. | Snake Henry | 30 | 537 | 1926 |
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